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Cigarette smoke-induced RANKL expression enhances MMP-9 production by alveolar macrophages

BACKGROUND AND PURPOSE: Cigarette smoke (CS) induces alveolar destruction through overproduction of proteinases including matrix metalloproteinase (MMP)-9 by alveolar macrophages (AMs). Receptor activator of nuclear factor-κB ligand (RANKL) functions in immune regulation and cytokine secretion; whet...

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Detalles Bibliográficos
Autores principales:	Zhou, Lu, Le, Yanqing, Tian, Jieyu, Yang, Xia, Jin, Rong, Gai, Xiaoyan, Sun, Yongchang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304243/ https://www.ncbi.nlm.nih.gov/pubmed/30587964 http://dx.doi.org/10.2147/COPD.S190023

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