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Overexpression of plasmepsin II and plasmepsin III does not directly cause reduction in Plasmodium falciparum sensitivity to artesunate, chloroquine and piperaquine

Artemisinin derivatives and their partner drugs in artemisinin combination therapies (ACTs) have played a pivotal role in global malaria mortality reduction during the last two decades. The loss of artemisinin efficacy due to evolving drug-resistant parasites could become a serious global health thr...

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Detalles Bibliográficos
Autores principales:	Loesbanluechai, Duangkamon, Kotanan, Namfon, de Cozar, Cristina, Kochakarn, Theerarat, Ansbro, Megan R., Chotivanich, Kesinee, White, Nicholas J., Wilairat, Prapon, Lee, Marcus C.S., Gamo, Francisco Javier, Sanz, Laura Maria, Chookajorn, Thanat, Kümpornsin, Krittikorn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304341/ https://www.ncbi.nlm.nih.gov/pubmed/30580023 http://dx.doi.org/10.1016/j.ijpddr.2018.11.004

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