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Trained Immunity-Based Vaccines: A New Paradigm for the Development of Broad-Spectrum Anti-infectious Formulations

Challenge with specific microbial stimuli induces long lasting epigenetic changes in innate immune cells that result in their enhanced response to a second challenge by the same or unrelated microbial insult, a process referred to as trained immunity. This opens a new avenue in vaccinology to develo...

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Detalles Bibliográficos
Autores principales:	Sánchez-Ramón, Silvia, Conejero, Laura, Netea, Mihai G., Sancho, David, Palomares, Óscar, Subiza, José Luis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304371/ https://www.ncbi.nlm.nih.gov/pubmed/30619296 http://dx.doi.org/10.3389/fimmu.2018.02936

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