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Proximity Ligation Assays for In Situ Detection of Innate Immune Activation: Focus on In Vitro-Transcribed mRNA
The characterization of innate immune activation is crucial for vaccine and therapeutic development, including RNA-based vaccines, a promising approach. Current measurement methods quantify type I interferon and inflammatory cytokine production, but they do not allow for the isolation of individual...
Autores principales: | Blanchard, Emmeline L., Loomis, Kristin H., Bhosle, Sushma M., Vanover, Daryll, Baumhof, Patrick, Pitard, Bruno, Zurla, Chiara, Santangelo, Philip J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304375/ https://www.ncbi.nlm.nih.gov/pubmed/30579042 http://dx.doi.org/10.1016/j.omtn.2018.11.002 |
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