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Selective Effects of mTOR Inhibitor Sirolimus on Naïve and CMV-Specific T Cells Extending Its Applicable Range Beyond Immunosuppression

Cytomegalovirus (CMV) infection/reactivation remains among the most important complications of immunosuppression after transplantation. However, recent clinical observations indicate that mammalian target of rapamycin (mTOR) inhibition with sirolimus may improve the outcome of CMV complications. Und...

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Detalles Bibliográficos
Autores principales:	Bak, Szilvia, Tischer, Sabine, Dragon, Anna, Ravens, Sarina, Pape, Lars, Koenecke, Christian, Oelke, Mathias, Blasczyk, Rainer, Maecker-Kolhoff, Britta, Eiz-Vesper, Britta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304429/ https://www.ncbi.nlm.nih.gov/pubmed/30619313 http://dx.doi.org/10.3389/fimmu.2018.02953

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