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Ascorbic acid reduces the genetic damage caused by miltefosine (hexadecylphosphocholine) in animals infected by Leishmania (Leishamnia) infantum without decreasing its antileishmanial activity

Leishamaniasis is a neglected disease caused by over 20 Leishmania species, occurring in more than a hundred countries. Miltefosine (hexadecylphosphocholine) is the single oral drug used in treatment for leshmaniases, including cases of infections resistant to pentavalent antimony. Our group has rec...

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Detalles Bibliográficos
Autores principales: Castelo-Branco, Patrícia Valéria, Alves, Hugo José, Pontes, Raissa Lacerda, Maciel-Silva, Vera Lucia, Ferreira Pereira, Silma Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304451/
https://www.ncbi.nlm.nih.gov/pubmed/30578864
http://dx.doi.org/10.1016/j.ijpddr.2018.12.002