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Competitive evolution of NSCLC tumor clones and the drug resistance mechanism of first-generation EGFR-TKIs in Chinese NSCLC patients

PURPOSE: Although many studies have reported on the resistance mechanism of first-generation EGFR TKIs (1(st) EGFR TKIs) treatment, large-scale dynamic ctDNA mutation analysis based on liquid biopsy for non-small cell lung cancer (NSCLC) in the Chinese population is rare. Using in-depth integration...

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Detalles Bibliográficos
Autores principales:	Deng, Qinfang, Xie, Boxiong, Wu, Leilei, Ji, Xianxiu, Li, Chao, Feng, Li, Fang, Qiyu, Bao, Yuchen, Li, Jialu, Jin, Shengnan, Ding, Chunming, Li, Yixue, Zhou, Songwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304452/ https://www.ncbi.nlm.nih.gov/pubmed/30603682 http://dx.doi.org/10.1016/j.heliyon.2018.e01031

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