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Sequential and synchronized hypertonicity-induced activation of Rel-family transcription factors is required for osmoprotection in renal cells

NF-κB and TonEBP belong to the Rel-superfamily of transcription factors. Several specific stimuli, including hypertonicity which is a key factor for renal physiology, are able to activate them. It has been reported that, after hypertonic challenge, NF-κB activity can be modulated by TonEBP, consider...

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Detalles Bibliográficos
Autores principales: Casali, Cecilia I., Erjavec, Luciana C., Fernández-Tome, María del Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304461/
https://www.ncbi.nlm.nih.gov/pubmed/30603705
http://dx.doi.org/10.1016/j.heliyon.2018.e01072