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Gallic Acid Attenuates Dimethylnitrosamine-Induced Liver Fibrosis by Alteration of Smad Phosphoisoform Signaling in Rats

Dimethylnitrosamine (DMN) is a potent hepatotoxin, carcinogen, and mutagen. In our previous study, a candidate gallic acid (GA) that widely exists in food and fruit was selected for its capability to alleviate DMN toxicity in vivo. We aimed to investigate the therapeutic potential of GA against DMN-...

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Detalles Bibliográficos
Autores principales: Chen, Yuxin, Zhou, Ziping, Mo, Qigui, Zhou, Gao, Wang, Youwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304566/
https://www.ncbi.nlm.nih.gov/pubmed/30627538
http://dx.doi.org/10.1155/2018/1682743