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Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development
Entamoeba histolytica is the responsible parasite of amoebiasis and remains one of the top three parasitic causes of mortality worldwide. With increased travel and emigration to developed countries, infection is becoming more common in nonendemic areas. Although the majority of individuals infected...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304615/ https://www.ncbi.nlm.nih.gov/pubmed/30631758 http://dx.doi.org/10.1155/2018/4601420 |
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author | Kantor, Micaella Abrantes, Anarella Estevez, Andrea Schiller, Alan Torrent, Jose Gascon, Jose Hernandez, Robert Ochner, Christopher |
author_facet | Kantor, Micaella Abrantes, Anarella Estevez, Andrea Schiller, Alan Torrent, Jose Gascon, Jose Hernandez, Robert Ochner, Christopher |
author_sort | Kantor, Micaella |
collection | PubMed |
description | Entamoeba histolytica is the responsible parasite of amoebiasis and remains one of the top three parasitic causes of mortality worldwide. With increased travel and emigration to developed countries, infection is becoming more common in nonendemic areas. Although the majority of individuals infected with E. histolytica remain asymptomatic, some present with amoebic colitis and disseminated disease. As more is learned about its pathogenesis and the host's immune response, the potential for developing a vaccine holds promise. This narrative review outlines the current knowledge regarding E. histolytica and E. dispar and insight in the development of a vaccine. |
format | Online Article Text |
id | pubmed-6304615 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-63046152019-01-10 Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development Kantor, Micaella Abrantes, Anarella Estevez, Andrea Schiller, Alan Torrent, Jose Gascon, Jose Hernandez, Robert Ochner, Christopher Can J Gastroenterol Hepatol Review Article Entamoeba histolytica is the responsible parasite of amoebiasis and remains one of the top three parasitic causes of mortality worldwide. With increased travel and emigration to developed countries, infection is becoming more common in nonendemic areas. Although the majority of individuals infected with E. histolytica remain asymptomatic, some present with amoebic colitis and disseminated disease. As more is learned about its pathogenesis and the host's immune response, the potential for developing a vaccine holds promise. This narrative review outlines the current knowledge regarding E. histolytica and E. dispar and insight in the development of a vaccine. Hindawi 2018-12-02 /pmc/articles/PMC6304615/ /pubmed/30631758 http://dx.doi.org/10.1155/2018/4601420 Text en Copyright © 2018 Micaella Kantor et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Kantor, Micaella Abrantes, Anarella Estevez, Andrea Schiller, Alan Torrent, Jose Gascon, Jose Hernandez, Robert Ochner, Christopher Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development |
title | Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development |
title_full | Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development |
title_fullStr | Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development |
title_full_unstemmed | Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development |
title_short | Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development |
title_sort | entamoeba histolytica: updates in clinical manifestation, pathogenesis, and vaccine development |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304615/ https://www.ncbi.nlm.nih.gov/pubmed/30631758 http://dx.doi.org/10.1155/2018/4601420 |
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