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Dexmedetomidine Ameliorates the Neurotoxicity of Sevoflurane on the Immature Brain Through the BMP/SMAD Signaling Pathway

Numerous studies have demonstrated that general anesthetics might damage the nervous system, thus, the effect of general anesthetics on the developing brain has attracted much attention. Dexmedetomidine (Dex) exhibits a certain neuroprotective effect, but the mechanism is obscure. In our study, preg...

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Detalles Bibliográficos
Autores principales: Shan, Yangyang, Yang, Fan, Tang, Zhiyin, Bi, Congjie, Sun, Shiwei, Zhang, Yongfang, Liu, Hongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304752/
https://www.ncbi.nlm.nih.gov/pubmed/30618586
http://dx.doi.org/10.3389/fnins.2018.00964