An O-Antigen Glycoconjugate Vaccine Produced Using Protein Glycan Coupling Technology Is Protective in an Inhalational Rat Model of Tularemia

There is a requirement for an efficacious vaccine to protect people against infection from Francisella tularensis, the etiological agent of tularemia. The lipopolysaccharide (LPS) of F. tularensis is suboptimally protective against a parenteral lethal challenge in mice. To develop a more efficacious...

Descripción completa

Detalles Bibliográficos
Autores principales: Marshall, Laura E., Nelson, Michelle, Davies, Carwyn H., Whelan, Adam O., Jenner, Dominic C., Moule, Madeleine G., Denman, Carmen, Cuccui, Jon, Atkins, Timothy P., Wren, Brendan W., Prior, Joann L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304830/
https://www.ncbi.nlm.nih.gov/pubmed/30622981
http://dx.doi.org/10.1155/2018/8087916

Ejemplares similares

Ejemplares similares