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Stress-Induced Hyperprolactinemia: Pathophysiology and Clinical Approach

While prolactin is most well known for its role in lactation and suppression of reproduction, its physiological functions are quite diverse. There are many etiologies of hyperprolactinemia, including physiologic as well as pathologic causes. Physiologic causes include pregnancy, lactation, sleep-ass...

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Detalles Bibliográficos
Autores principales: Levine, Samara, Muneyyirci-Delale, Ozgul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304861/
https://www.ncbi.nlm.nih.gov/pubmed/30627169
http://dx.doi.org/10.1155/2018/9253083
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author Levine, Samara
Muneyyirci-Delale, Ozgul
author_facet Levine, Samara
Muneyyirci-Delale, Ozgul
author_sort Levine, Samara
collection PubMed
description While prolactin is most well known for its role in lactation and suppression of reproduction, its physiological functions are quite diverse. There are many etiologies of hyperprolactinemia, including physiologic as well as pathologic causes. Physiologic causes include pregnancy, lactation, sleep-associated, nipple stimulation and sexual orgasm, chest wall stimulation, or trauma. Stress is also an important physiologic cause of hyperprolactinemia, and its clinical significance is still being explored. This review will provide an overview of prolactin physiology, the role of stress in prolactin secretion, as well as the general clinical approach to hyperprolactinemia.
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spelling pubmed-63048612019-01-09 Stress-Induced Hyperprolactinemia: Pathophysiology and Clinical Approach Levine, Samara Muneyyirci-Delale, Ozgul Obstet Gynecol Int Review Article While prolactin is most well known for its role in lactation and suppression of reproduction, its physiological functions are quite diverse. There are many etiologies of hyperprolactinemia, including physiologic as well as pathologic causes. Physiologic causes include pregnancy, lactation, sleep-associated, nipple stimulation and sexual orgasm, chest wall stimulation, or trauma. Stress is also an important physiologic cause of hyperprolactinemia, and its clinical significance is still being explored. This review will provide an overview of prolactin physiology, the role of stress in prolactin secretion, as well as the general clinical approach to hyperprolactinemia. Hindawi 2018-12-03 /pmc/articles/PMC6304861/ /pubmed/30627169 http://dx.doi.org/10.1155/2018/9253083 Text en Copyright © 2018 Samara Levine and Ozgul Muneyyirci-Delale. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Levine, Samara
Muneyyirci-Delale, Ozgul
Stress-Induced Hyperprolactinemia: Pathophysiology and Clinical Approach
title Stress-Induced Hyperprolactinemia: Pathophysiology and Clinical Approach
title_full Stress-Induced Hyperprolactinemia: Pathophysiology and Clinical Approach
title_fullStr Stress-Induced Hyperprolactinemia: Pathophysiology and Clinical Approach
title_full_unstemmed Stress-Induced Hyperprolactinemia: Pathophysiology and Clinical Approach
title_short Stress-Induced Hyperprolactinemia: Pathophysiology and Clinical Approach
title_sort stress-induced hyperprolactinemia: pathophysiology and clinical approach
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304861/
https://www.ncbi.nlm.nih.gov/pubmed/30627169
http://dx.doi.org/10.1155/2018/9253083
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