Folate deficiency drives mitotic missegregation of the human FRAXA locus

The instability of chromosome fragile sites is implicated as a causative factor in several human diseases, including cancer [for common fragile sites (CFSs)] and neurological disorders [for rare fragile sites (RFSs)]. Previous studies have indicated that problems arising during DNA replication are t...

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Detalles Bibliográficos
Autores principales: Bjerregaard, Victoria A., Garribba, Lorenza, McMurray, Cynthia T., Hickson, Ian D., Liu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304931/
https://www.ncbi.nlm.nih.gov/pubmed/30509972
http://dx.doi.org/10.1073/pnas.1808377115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304931/
https://www.ncbi.nlm.nih.gov/pubmed/30509972
http://dx.doi.org/10.1073/pnas.1808377115

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