Cargando…
Integrated landscape of copy number variation and RNA expression associated with nodal metastasis in invasive ductal breast carcinoma
BACKGROUND: Lymph node metastasis (NM) in breast cancer is a clinical predictor of patient outcomes, but how its genetic underpinnings contribute to aggressive phenotypes is unclear. Our objective was to create the first landscape analysis of CNV-associated NM in ductal breast cancer. To assess the...
Autores principales: | Behring, Michael, Shrestha, Sadeep, Manne, Upender, Cui, Xiangqin, Gonzalez-Reymundez, Agustin, Grueneberg, Alexander, Vazquez, Ana I. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305147/ https://www.ncbi.nlm.nih.gov/pubmed/30627325 http://dx.doi.org/10.18632/oncotarget.26386 |
Ejemplares similares
-
Gain of function in somatic TP53 mutations is associated with immune‐rich breast tumors and changes in tumor‐associated macrophages
por: Behring, Michael, et al.
Publicado: (2019) -
Immunophenotype‐associated gene signature in ductal breast tumors varies by receptor subtype, but the expression of individual signature genes remains consistent
por: Behring, Michael, et al.
Publicado: (2021) -
Variations in CCL3L gene cluster sequence and non-specific gene copy numbers
por: Shrestha, Sadeep, et al.
Publicado: (2010) -
Age-Dependent Heterogeneity of Lymph Node Metastases and Survival Identified by Analysis of a National Breast Cancer Registry
por: Behring, Michael, et al.
Publicado: (2022) -
MOSS: multi-omic integration with sparse value decomposition
por: Gonzalez-Reymundez, Agustin, et al.
Publicado: (2022)