Cargando…
Anergy into T regulatory cells: an integration of metabolic cues and epigenetic changes at the Foxp3 conserved non-coding sequence 2
Peripheral immune self-tolerance relies on protective mechanisms to control autoreactive T cells that escape deletion in the thymus. Suppression of autoreactive lymphocytes is necessary to avoid autoimmunity and immune cell–mediated damage of healthy tissues. An intriguing relationship has emerged b...
Autores principales: | Silva Morales, Milagros, Mueller, Daniel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305231/ https://www.ncbi.nlm.nih.gov/pubmed/30613389 http://dx.doi.org/10.12688/f1000research.16551.1 |
Ejemplares similares
-
Self and microbiota-derived epitopes induce CD4(+) T cell anergy and conversion into CD4(+)Foxp3(+) regulatory cells
por: Kuczma, Michal P., et al.
Publicado: (2020) -
Epigenetic Control of the foxp3 Locus in Regulatory T Cells
por: Floess, Stefan, et al.
Publicado: (2007) -
Development of Foxp3+ regulatory T cell: epigenetics and more…
por: Hühn, Jochen
Publicado: (2011) -
Pregnancy imprints regulatory memory that sustains anergy to fetal antigen
por: Rowe, Jared H., et al.
Publicado: (2012) -
CD4(+) T cell anergy prevents autoimmunity and generates regulatory T cell precursors
por: Kalekar, Lokesh A., et al.
Publicado: (2016)