Cargando…

Anergy into T regulatory cells: an integration of metabolic cues and epigenetic changes at the Foxp3 conserved non-coding sequence 2

Peripheral immune self-tolerance relies on protective mechanisms to control autoreactive T cells that escape deletion in the thymus. Suppression of autoreactive lymphocytes is necessary to avoid autoimmunity and immune cell–mediated damage of healthy tissues. An intriguing relationship has emerged b...

Descripción completa

Detalles Bibliográficos
Autores principales: Silva Morales, Milagros, Mueller, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305231/
https://www.ncbi.nlm.nih.gov/pubmed/30613389
http://dx.doi.org/10.12688/f1000research.16551.1

Ejemplares similares