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Epigenetic changes around the pX region and spontaneous HTLV-1 transcription are CTCF-independent
Background: The human retrovirus HTLV-1 inserts the viral complementary DNA of 9 kb into the host genome. Both plus- and minus-strands of the provirus are transcribed, respectively from the 5′ and 3′ long terminal repeats (LTR). Plus-strand expression is rapid and intense once activated, whereas the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305241/ https://www.ncbi.nlm.nih.gov/pubmed/30607369 http://dx.doi.org/10.12688/wellcomeopenres.14741.2 |