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Neutrophils From Children With Systemic Juvenile Idiopathic Arthritis Exhibit Persistent Proinflammatory Activation Despite Long-Standing Clinically Inactive Disease

Background: Systemic juvenile idiopathic arthritis (SJIA) is a chronic childhood arthropathy with features of autoinflammation. Early inflammatory SJIA is associated with expansion and activation of neutrophils with a sepsis-like phenotype, but neutrophil phenotypes present in longstanding and clini...

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Detalles Bibliográficos
Autores principales: Brown, Rachel A., Henderlight, Maggie, Do, Thuy, Yasin, Shima, Grom, Alexei A., DeLay, Monica, Thornton, Sherry, Schulert, Grant S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305285/
https://www.ncbi.nlm.nih.gov/pubmed/30619348
http://dx.doi.org/10.3389/fimmu.2018.02995

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