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Oligosaccharide Chromatographic Techniques for Quantitation of Structural Process-Related Impurities in Heparin Resulting From 2-O Desulfation

Heparin is a widely-used intravenous anticoagulant comprising a complex mixture of highly-sulfated linear polysaccharides of repeating sequences of uronic acids (either iduronic or glucuronic) 1->4 linked to D-glucosamine with specific sulfation patterns. Preparation of crude heparin from mammali...

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Detalles Bibliográficos
Autores principales:	Anger, Pascal, Martinez, Céline, Mourier, Pierre, Viskov, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305297/ https://www.ncbi.nlm.nih.gov/pubmed/30619858 http://dx.doi.org/10.3389/fmed.2018.00346

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