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Surfactant Protein D Deficiency Aggravates Cigarette Smoke-Induced Lung Inflammation by Upregulation of Ceramide Synthesis

Cigarette smoke (CS) is the main cause of chronic obstructive pulmonary disease. Surfactant protein D (SP-D) is an important anti-inflammatory protein that regulates host immune defense in the lungs. Here, we investigated the role of SP-D in a murine model of CS-induced inflammation. Pulmonary SP-D...

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Detalles Bibliográficos
Autores principales:	Pilecki, Bartosz, Wulf-Johansson, Helle, Støttrup, Christian, Jørgensen, Patricia Troest, Djiadeu, Pascal, Nexøe, Anders Bathum, Schlosser, Anders, Hansen, Søren Werner Karlskov, Madsen, Jens, Clark, Howard William, Nielsen, Claus Henrik, Vestbo, Jørgen, Palaniyar, Nades, Holmskov, Uffe, Sorensen, Grith Lykke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305334/ https://www.ncbi.nlm.nih.gov/pubmed/30619359 http://dx.doi.org/10.3389/fimmu.2018.03013

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