Cargando…

Ca(2+)-Dependent Transcriptional Repressors KCNIP and Regulation of Prognosis Genes in Glioblastoma

Glioblastomas (GBMs) are the most aggressive and lethal primary astrocytic tumors in adults, with very poor prognosis. Recurrence in GBM is attributed to glioblastoma stem-like cells (GSLCs). The behavior of the tumor, including proliferation, progression, invasion, and significant resistance to the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Néant, Isabelle, Haiech, Jacques, Kilhoffer, Marie-Claude, Aulestia, Francisco J., Moreau, Marc, Leclerc, Catherine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305344/ https://www.ncbi.nlm.nih.gov/pubmed/30618619 http://dx.doi.org/10.3389/fnmol.2018.00472

Ejemplares similares

Quiescence status of glioblastoma stem-like cells involves remodelling of Ca(2+) signalling and mitochondrial shape
por: Aulestia, Francisco J., et al.
Publicado: (2018)

Personalized medicine and education: the challenge
por: Haiech, Jacques, et al.
Publicado: (2012)

The calcium: an early signal that initiates the formation of the nervous system during embryogenesis
por: Leclerc, Catherine, et al.
Publicado: (2012)

Trpc1 as the Missing Link Between the Bmp and Ca(2+) Signalling Pathways During Neural Specification in Amphibians
por: Néant, Isabelle, et al.
Publicado: (2019)

Cancer Stem Cell Quiescence and Plasticity as Major Challenges in Cancer Therapy
por: Chen, Wanyin, et al.
Publicado: (2016)

Early calcium increase triggers the formation of olfactory long-term memory in honeybees
por: Perisse, Emmanuel, et al.
Publicado: (2009)

Integration of Mouse and Human Genome-Wide Association Data Identifies KCNIP4 as an Asthma Gene
por: Himes, Blanca E., et al.
Publicado: (2013)

Global Gene Knockout of Kcnip3 Enhances Pain Sensitivity and Exacerbates Negative Emotions in Rats
por: Guo, Yu-Peng, et al.
Publicado: (2019)

Inhibitory Kcnip2 neurons of the spinal dorsal horn control behavioral sensitivity to environmental cold
por: Albisetti, Gioele W., et al.
Publicado: (2023)

Comparative Expression Study of the Endo–G Protein Coupled Receptor (GPCR) Repertoire in Human Glioblastoma Cancer Stem-like Cells, U87-MG Cells and Non Malignant Cells of Neural Origin Unveils New Potential Therapeutic Targets
por: Fève, Marie, et al.
Publicado: (2014)

A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough
por: Mosley, J D, et al.
Publicado: (2016)

Genome-wide screening identifies a KCNIP1 copy number variant as a genetic predictor for atrial fibrillation
por: Tsai, Chia-Ti, et al.
Publicado: (2016)

The anti‐hypertensive drug prazosin inhibits glioblastoma growth via the PKCδ‐dependent inhibition of the AKT pathway
por: Assad Kahn, Suzana, et al.
Publicado: (2016)

WNK1 kinase and its partners Akt, SGK1 and NBC-family Na(+)/HCO3(−) cotransporters are potential therapeutic targets for glioblastoma stem-like cells linked to Bisacodyl signaling
por: Chen, Wanyin, et al.
Publicado: (2018)

Characterisation of canine KCNIP4: A novel gene for cerebellar ataxia identified by whole-genome sequencing two affected Norwegian Buhund dogs
por: Jenkins, Christopher A., et al.
Publicado: (2020)

Chemical Library Screening and Structure-Function Relationship Studies Identify Bisacodyl as a Potent and Selective Cytotoxic Agent Towards Quiescent Human Glioblastoma Tumor Stem-Like Cells
por: Zeniou, Maria, et al.
Publicado: (2015)

REST is a hypoxia-responsive transcriptional repressor
por: Cavadas, Miguel A. S., et al.
Publicado: (2016)

Chimeric NANOG repressors inhibit glioblastoma growth in vivo in a context-dependent manner
por: Kuciak, Monika, et al.
Publicado: (2019)

Bcl-6 is the nexus transcription factor of T follicular helper cells (T(FH)) via repressor-of-repressor circuits
por: Choi, Jinyong, et al.
Publicado: (2020)

Crystal structure of the transcriptional repressor DdrO: insight into the metalloprotease/repressor-controlled radiation response in Deinococcus
por: de Groot, Arjan, et al.
Publicado: (2019)

Human SLFN5 is a Transcriptional Co-repressor of STAT1-Mediated Interferon Responses and Promotes the Malignant Phenotype in Glioblastoma
por: Arslan, Ahmet Dirim, et al.
Publicado: (2017)

A Role for Dendritic Translation of CaMKIIα mRNA in Olfactory Plasticity
por: Néant-Fery, Marie, et al.
Publicado: (2012)

Treponema denticola TroR is a manganese- and iron-dependent transcriptional repressor
por: Brett, Paul J, et al.
Publicado: (2008)

Generation and Behavior Characterization of CaMKIIβ Knockout Mice
por: Bachstetter, Adam D., et al.
Publicado: (2014)

A labile transcriptional repressor modulates endotoxin tolerance
Publicado: (1994)

Identification of the gene transcription repressor domain of Gli3
por: Tsanev, Robert, et al.
Publicado: (2009)

Glycine decarboxylase is a target for transcriptional repressor Snail
por: Chen, Guohua, et al.
Publicado: (2014)

The Transcriptional Repressor Domain of Gli3 Is Intrinsically Disordered
por: Tsanev, Robert, et al.
Publicado: (2013)

Homodimerization of the Death-Associated Protein Kinase Catalytic Domain: Development of a New Small Molecule Fluorescent Reporter
por: Zimmermann, Michael, et al.
Publicado: (2010)

EGR1 Functions as a Potent Repressor of MEF2 Transcriptional Activity
por: Feng, Yi, et al.
Publicado: (2015)

MAF1 is a chronic repressor of RNA polymerase III transcription in the mouse
por: Bonhoure, Nicolas, et al.
Publicado: (2020)

The transcriptional repressor Hes1 attenuates inflammation via regulating transcriptional elongation
por: Shang, Yingli, et al.
Publicado: (2016)

DNA-dependent conversion of Oct-1 and Oct-2 into transcriptional repressors by Groucho/TLE
por: Malin, Stephen, et al.
Publicado: (2005)

DNMT1 interacts with the developmental transcriptional repressor HESX1
por: Sajedi, Ezat, et al.
Publicado: (2008)

Nlz1/Znf703 acts as a repressor of transcription
por: Nakamura, Mako, et al.
Publicado: (2008)

Negative regulation of osteoclastogenesis and bone resorption by cytokines and transcriptional repressors
por: Zhao, Baohong, et al.
Publicado: (2011)

Identification of DBC1 as a transcriptional repressor for BRCA1
por: Hiraike, H, et al.
Publicado: (2010)

The transcriptional repressor NKAP is required for the development of iNKT cells
por: Thapa, Puspa, et al.
Publicado: (2013)

Implication of intracellular localization of transcriptional repressor PLZF in thyroid neoplasms
por: Matsuzawa, Kazuhiko, et al.
Publicado: (2014)

The Influence of Repressor DNA Binding Site Architecture on Transcriptional Control
por: Park, Dan M., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_scrsrnl1n20brgrt4jh86oefk3