Linagliptin Attenuates the Cardiac Dysfunction Associated With Experimental Sepsis in Mice With Pre-existing Type 2 Diabetes by Inhibiting NF-κB

The mortality rate of patients who develop sepsis-related cardiac dysfunction is high. Many disease conditions (e.g., diabetes) increase the susceptibility to infections and subsequently sepsis. Activation of the NF-κB pathway plays a crucial role in the pathophysiology of sepsis-associated cardiac...

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Detalles Bibliográficos
Autores principales: Al Zoubi, Sura, Chen, Jianmin, Murphy, Catherine, Martin, Lukas, Chiazza, Fausto, Collotta, Debora, Yaqoob, Muhammad M., Collino, Massimo, Thiemermann, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305440/
https://www.ncbi.nlm.nih.gov/pubmed/30619349
http://dx.doi.org/10.3389/fimmu.2018.02996

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