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Orexin Depolarizes Central Amygdala Neurons via Orexin Receptor 1, Phospholipase C and Sodium-Calcium Exchanger and Modulates Conditioned Fear

Orexins (OX), also known as hypocretins, are excitatory neuropeptides with well-described roles in regulation of wakefulness, arousal, energy homeostasis, and anxiety. An additional and recently recognized role of OX is modulation of fear responses. We studied the OX neurons of the perifornical hypo...

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Detalles Bibliográficos
Autores principales: Dustrude, Erik T., Caliman, Izabela F., Bernabe, Cristian S., Fitz, Stephanie D., Grafe, Laura A., Bhatnagar, Seema, Bonaventure, Pascal, Johnson, Philip L., Molosh, Andrei I., Shekhar, Anantha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305451/
https://www.ncbi.nlm.nih.gov/pubmed/30618563
http://dx.doi.org/10.3389/fnins.2018.00934