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Orexin Depolarizes Central Amygdala Neurons via Orexin Receptor 1, Phospholipase C and Sodium-Calcium Exchanger and Modulates Conditioned Fear
Orexins (OX), also known as hypocretins, are excitatory neuropeptides with well-described roles in regulation of wakefulness, arousal, energy homeostasis, and anxiety. An additional and recently recognized role of OX is modulation of fear responses. We studied the OX neurons of the perifornical hypo...
Autores principales: | Dustrude, Erik T., Caliman, Izabela F., Bernabe, Cristian S., Fitz, Stephanie D., Grafe, Laura A., Bhatnagar, Seema, Bonaventure, Pascal, Johnson, Philip L., Molosh, Andrei I., Shekhar, Anantha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305451/ https://www.ncbi.nlm.nih.gov/pubmed/30618563 http://dx.doi.org/10.3389/fnins.2018.00934 |
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