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Sex Bias in Asthma Prevalence and Pathogenesis
Sex-related differences in asthma prevalence are well established and change through the reproductive phases of life. As children, boys have increased prevalence of asthma compared to girls. However, as adults, women have increased prevalence of asthma compared to men. Many factors, including geneti...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305471/ https://www.ncbi.nlm.nih.gov/pubmed/30619350 http://dx.doi.org/10.3389/fimmu.2018.02997 |
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author | Shah, Ruchi Newcomb, Dawn C. |
author_facet | Shah, Ruchi Newcomb, Dawn C. |
author_sort | Shah, Ruchi |
collection | PubMed |
description | Sex-related differences in asthma prevalence are well established and change through the reproductive phases of life. As children, boys have increased prevalence of asthma compared to girls. However, as adults, women have increased prevalence of asthma compared to men. Many factors, including genetics, environment, immunological responses, and sex hormones, affect the sex disparity associated with the development and control of asthma and other allergic diseases. Fluctuations of hormones during puberty, menstruation, pregnancy, and menopause, alter asthma symptoms and severity. In this article, we review clinical and epidemiological studies that examined the sex disparity in asthma and other allergic diseases as well as the role of sex hormones on asthma pathogenesis. |
format | Online Article Text |
id | pubmed-6305471 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-63054712019-01-07 Sex Bias in Asthma Prevalence and Pathogenesis Shah, Ruchi Newcomb, Dawn C. Front Immunol Immunology Sex-related differences in asthma prevalence are well established and change through the reproductive phases of life. As children, boys have increased prevalence of asthma compared to girls. However, as adults, women have increased prevalence of asthma compared to men. Many factors, including genetics, environment, immunological responses, and sex hormones, affect the sex disparity associated with the development and control of asthma and other allergic diseases. Fluctuations of hormones during puberty, menstruation, pregnancy, and menopause, alter asthma symptoms and severity. In this article, we review clinical and epidemiological studies that examined the sex disparity in asthma and other allergic diseases as well as the role of sex hormones on asthma pathogenesis. Frontiers Media S.A. 2018-12-18 /pmc/articles/PMC6305471/ /pubmed/30619350 http://dx.doi.org/10.3389/fimmu.2018.02997 Text en Copyright © 2018 Shah and Newcomb. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Immunology Shah, Ruchi Newcomb, Dawn C. Sex Bias in Asthma Prevalence and Pathogenesis |
title | Sex Bias in Asthma Prevalence and Pathogenesis |
title_full | Sex Bias in Asthma Prevalence and Pathogenesis |
title_fullStr | Sex Bias in Asthma Prevalence and Pathogenesis |
title_full_unstemmed | Sex Bias in Asthma Prevalence and Pathogenesis |
title_short | Sex Bias in Asthma Prevalence and Pathogenesis |
title_sort | sex bias in asthma prevalence and pathogenesis |
topic | Immunology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305471/ https://www.ncbi.nlm.nih.gov/pubmed/30619350 http://dx.doi.org/10.3389/fimmu.2018.02997 |
work_keys_str_mv | AT shahruchi sexbiasinasthmaprevalenceandpathogenesis AT newcombdawnc sexbiasinasthmaprevalenceandpathogenesis |