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Therapeutic Effect of the Substrate-Selective COX-2 Inhibitor IMMA in the Animal Model of Chronic Constriction Injury
Enhancement of endocannabinoid signaling has emerged as an attractive strategy for the treatment of pain. In addition to the well-characterized hydrolytic pathways, cyclooxygenase-2 (COX-2) mediated oxygenation is thought to be an alternative route for endocannabinoid metabolism and therefore provid...
Autores principales: | Jones, Melissa, Wen, Jie, Selvaraj, Prabhuanand, Tanaka, Mikiei, Moran, Sean, Zhang, Yumin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305478/ https://www.ncbi.nlm.nih.gov/pubmed/30618769 http://dx.doi.org/10.3389/fphar.2018.01481 |
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