OATP1B3 (699G>A) and CYP2C9*2, *3 significantly influenced the transport and metabolism of glibenclamide and glipizide

Glibenclamide and glipizide show large substantial inter-individual variation in clinical efficacy, which may be resulted from the genetic differences of metabolic enzymes and transporters in individuals. This study purposed to investigate the effect of OATP1B3 and CYP2C9 genetic polymorphisms on th...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Fayou, Liu, Linlin, Chen, Lin, Liu, Mingyi, Liu, Fanglan, Xiong, Yuqing, Hu, Xiao, Xia, Chunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305483/
https://www.ncbi.nlm.nih.gov/pubmed/30584236
http://dx.doi.org/10.1038/s41598-018-36212-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305483/
https://www.ncbi.nlm.nih.gov/pubmed/30584236
http://dx.doi.org/10.1038/s41598-018-36212-7

Ejemplares similares