Cargando…

OATP1B3 (699G>A) and CYP2C92, 3 significantly influenced the transport and metabolism of glibenclamide and glipizide

Glibenclamide and glipizide show large substantial inter-individual variation in clinical efficacy, which may be resulted from the genetic differences of metabolic enzymes and transporters in individuals. This study purposed to investigate the effect of OATP1B3 and CYP2C9 genetic polymorphisms on th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Fayou, Liu, Linlin, Chen, Lin, Liu, Mingyi, Liu, Fanglan, Xiong, Yuqing, Hu, Xiao, Xia, Chunhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305483/ https://www.ncbi.nlm.nih.gov/pubmed/30584236 http://dx.doi.org/10.1038/s41598-018-36212-7

Ejemplares similares

CYP2C9 and OATP1B1 genetic polymorphisms affect the metabolism and transport of glimepiride and gliclazide
por: Yang, Fayou, et al.
Publicado: (2018)

Ginsenoside Rb1 and Rd Remarkably Inhibited the Hepatic Uptake of Ophiopogonin D in Shenmai Injection Mediated by OATPs/oatps
por: Liu, Xiaopei, et al.
Publicado: (2018)

Structure of human drug transporters OATP1B1 and OATP1B3
por: Ciută, Anca-Denise, et al.
Publicado: (2023)

Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1
por: Nies, Anne T, et al.
Publicado: (2013)

Effects of vercirnon on the activity of CYP3A4, CYP2C19 and CYP2C8 enzymes and BCRP and OATP1B1 transporters using probe substrates
por: Haberer, Lynda J., et al.
Publicado: (2013)

Berberine Promotes OATP1B1 Expression and Rosuvastatin Uptake by Inducing Nuclear Translocation of FXR and LXRα
por: Liu, Mingyi, et al.
Publicado: (2020)

Regulation of Organic Anion Transporting Polypeptides (OATP) 1B1- and OATP1B3-Mediated Transport: An Updated Review in the Context of OATP-Mediated Drug-Drug Interactions
por: Alam, Khondoker, et al.
Publicado: (2018)

Interaction of Antifungal Drugs with CYP3A- and OATP1B-Mediated Venetoclax Elimination
por: Eisenmann, Eric D., et al.
Publicado: (2022)

Itraconazole-Induced Increases in Gilteritinib Exposure Are Mediated by CYP3A and OATP1B
por: Garrison, Dominique A., et al.
Publicado: (2022)

Differential Preincubation Effects of Nicardipine on OATP1B1- and OATP1B3-Mediated Transport in the Presence and Absence of Protein: Implications in Assessing OATP1B1- and OATP1B3-Mediated Drug–Drug Interactions
por: Kayesh, Ruhul, et al.
Publicado: (2023)

SUN-185 Glipizide Induced Hepatotoxicity
por: Kamal, Palwasha, et al.
Publicado: (2019)

Organic Anion Transporting Polypeptide (OATP) 1B3 is a Significant Transporter for Hepatic Uptake of Conjugated Bile Acids in Humans
por: Pan, Qiong, et al.
Publicado: (2023)

Effect of Rifampin‐Mediated OATP1B1 and OATP1B3 Transporter Inhibition on the Pharmacokinetics of the P2Y12 Receptor Antagonist Selatogrel
por: Schilling, Uta, et al.
Publicado: (2020)

Effect of uptake transporters OAT3 and OATP1B1 and efflux transporter MRP2 on the pharmacokinetics of eluxadoline
por: Davenport, J Michael, et al.
Publicado: (2015)

Organic anion transporting polypeptides OATP1B1 and OATP1B3 and their genetic variants influence the pharmacokinetics and pharmacodynamics of raloxifene
por: Trdan Lušin, Tina, et al.
Publicado: (2012)

Transcriptional Regulation of Liver-Type OATP1B3 (Lt-OATP1B3) and Cancer-Type OATP1B3 (Ct-OATP1B3) Studied in Hepatocyte-Derived and Colon Cancer-Derived Cell Lines
por: Haberkorn, Bastian, et al.
Publicado: (2023)

Oleanolic Acid and Ursolic Acid Induce UGT1A1 Expression in HepG2 Cells by Activating PXR Rather Than CAR
por: Yao, Na, et al.
Publicado: (2019)

Luminol–K(3)Fe(CN)(6) chemiluminescence system for the determination of glipizide
por: Chen, Xin, et al.
Publicado: (2013)

Formulation and Characterization of Mucoadhesive Buccal Films of Glipizide
por: Semalty, Mona, et al.
Publicado: (2008)

An unusual case of glipizide-induced proximal myopathy
por: Das, Saibal, et al.
Publicado: (2016)

The Physico-Chemical Properties of Glipizide: New Findings
por: Bruni, Giovanna, et al.
Publicado: (2021)

Effect of Chronic Kidney Disease on Nonrenal Elimination Pathways: A Systematic Assessment of CYP1A2, CYP2C8, CYP2C9, CYP2C19, and OATP
por: Tan, Ming‐Liang, et al.
Publicado: (2017)

Montelukast Disposition: No Indication of Transporter-Mediated Uptake in OATP2B1 and OATP1B1 Expressing HEK293 Cells
por: Brännström, Marie, et al.
Publicado: (2015)

Inhibitory Effects of Green Tea and (–)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein
por: Knop, Jana, et al.
Publicado: (2015)

8-Deoxy-Rifamycin Derivatives from Amycolatopsis mediterranei S699 ΔrifT Strain
por: Ye, Feng, et al.
Publicado: (2020)

Drug Transporters ABCB1 (P-gp) and OATP, but not Drug-Metabolizing Enzyme CYP3A4, Affect the Pharmacokinetics of the Psychoactive Alkaloid Ibogaine and its Metabolites
por: F. Martins, Margarida L., et al.
Publicado: (2022)

Risk of Developing Hepatocellular Carcinoma following Depressive Disorder Based on the Expression Level of Oatp2a1 and Oatp2b1
por: Chen, Yan, et al.
Publicado: (2019)

Preparation, characterization and optimization of glipizide controlled release nanoparticles
por: Emami, J., et al.
Publicado: (2014)

Rifamycin W Analogues from Amycolatopsis mediterranei S699 Δrif-orf5 Strain
por: Shi, Yanrong, et al.
Publicado: (2021)

Adult Gli2(+/–);Gli3(Δ699/+) Male and Female Mice Display a Spectrum of Genital Malformation
por: He, Fei, et al.
Publicado: (2016)

FRI699 Hyperphosphatemia In The Setting Of Sodium Hypochlorite Use
por: Champagne, Kareen, et al.
Publicado: (2023)

Comprehensive PBPK Model of Rifampicin for Quantitative Prediction of Complex Drug‐Drug Interactions: CYP3A/2C9 Induction and OATP Inhibition Effects
por: Asaumi, Ryuta, et al.
Publicado: (2018)

Glipizide, an antidiabetic drug, suppresses tumor growth and metastasis by inhibiting angiogenesis
por: Qi, Cuiling, et al.
Publicado: (2014)

Results From Drug–Drug Interaction Studies In Vitro and In Vivo Investigating the Inhibitory Effect of Finerenone on the Drug Transporters BCRP, OATP1B1, and OATP1B3
por: Heinig, Roland, et al.
Publicado: (2022)

Localization of organic anion transporting polypeptide (Oatp) 1a4 and Oatp1c1 at the rat blood-retinal barrier
por: Akanuma, Shin-ichi, et al.
Publicado: (2013)

Effects of Metformin Versus Glipizide on Cardiovascular Outcomes in Patients With Type 2 Diabetes and Coronary Artery Disease
por: Hong, Jie, et al.
Publicado: (2013)

Selectivity and Potency of Microcystin Congeners against OATP1B1 and OATP1B3 Expressing Cancer Cells
por: Niedermeyer, Timo H. J., et al.
Publicado: (2014)

Role of OATP1B1 and OATP1B3 in Drug-Drug Interactions Mediated by Tyrosine Kinase Inhibitors
por: Garrison, Dominique A., et al.
Publicado: (2020)

Clarithromycin and Glipizide Drug-drug Interaction Leading to Refractory Hypoglycemia
por: Ruan, Xu Cong, et al.
Publicado: (2019)

Glycine 699 is pivotal for the motor activity of skeletal muscle myosin
Publicado: (1996)

Cannot write session to /tmp/vufind_sessions/sess_5hi3rfqmfoskjno5ntnjqolnca