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UPR Induction Prevents Iron Accumulation and Oligodendrocyte Loss in ex vivo Cultured Hippocampal Slices

The accumulation of iron within the brain occurs in many chronic disorders including Alzheimer’s and Parkinson’s disease and multiple sclerosis. Outside the CNS, a link between levels of iron and the unfolded protein response has already been established. To determine if such a relationship operates...

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Detalles Bibliográficos
Autores principales: Healy, Sinead, McMahon, Jill, FitzGerald, Una
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305600/
https://www.ncbi.nlm.nih.gov/pubmed/30618588
http://dx.doi.org/10.3389/fnins.2018.00969

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