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Dopamine Autoxidation Is Controlled by Acidic pH

We studied the reaction mechanism of dopamine autoxidation using quantum chemical methods. Unlike other biogenic amines important in the central nervous system, dopamine and noradrenaline are capable of undergoing a non-enzymatic autoxidative reaction giving rise to a superoxide anion that further d...

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Detalles Bibliográficos
Autores principales: Umek, Nejc, Geršak, Blaž, Vintar, Neli, Šoštarič, Maja, Mavri, Janez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305604/
https://www.ncbi.nlm.nih.gov/pubmed/30618616
http://dx.doi.org/10.3389/fnmol.2018.00467