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Genomic landscape and mutational impacts of recurrently mutated genes in cancers

BACKGROUND: Cancer genes tend to be highly mutated under positive selection. Better understanding the recurrently mutated genes (RMGs) in cancer is critical for explicating the mechanisms of tumorigenesis and providing vital clues for therapy. Although some studies have investigated functional impac...

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Detalles Bibliográficos
Autores principales: Liu, Baolin, Hu, Fei‐Fei, Zhang, Qiong, Hu, Hui, Ye, Zheng, Tang, Qin, Guo, An‐Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305651/
https://www.ncbi.nlm.nih.gov/pubmed/30107644
http://dx.doi.org/10.1002/mgg3.458