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Molecular characterization of PRKN structural variations identified through whole‐genome sequencing

BACKGROUND: Early‐onset Parkinson's disease (PD) is the most common inherited form of parkinsonism, with the PRKN gene being the most frequently identified mutated. Exon rearrangements, identified in about 43.2% of the reported PD patients and with higher frequency in specific ethnicities, are...

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Detalles Bibliográficos
Autores principales:	Bravo, Paloma, Darvish, Hossein, Tafakhori, Abbas, Azcona, Luis J., Johari, Amir Hossein, Jamali, Faezeh, Paisán‐Ruiz, Coro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Clinical Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305656/ https://www.ncbi.nlm.nih.gov/pubmed/30328284 http://dx.doi.org/10.1002/mgg3.482

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