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Hepatocyte-Derived Lipotoxic Extracellular Vesicle Sphingosine 1-Phosphate Induces Macrophage Chemotaxis

Background: The pathophysiology of non-alcoholic steatohepatitis involves hepatocyte lipotoxicity due to excess saturated free fatty acids and concomitant proinflammatory macrophage effector responses. These include the infiltration of macrophages into hepatic cords in response to incompletely under...

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Detalles Bibliográficos
Autores principales:	Liao, Chieh-Yu, Song, Myeong Jun, Gao, Yandong, Mauer, Amy S., Revzin, Alexander, Malhi, Harmeet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305739/ https://www.ncbi.nlm.nih.gov/pubmed/30619336 http://dx.doi.org/10.3389/fimmu.2018.02980

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