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Using Integrative Analysis of DNA Methylation and Gene Expression Data in Multiple Tissue Types to Prioritize Candidate Genes for Drug Development in Obesity
Obesity has become a major public health issue which is caused by a combination of genetic and environmental factors. Genome-wide DNA methylation studies have identified that DNA methylation at Cytosine-phosphate-Guanine (CpG) sites are associated with obesity. However, subsequent functional validat...
Autores principales: | Guo, Qingjie, Zheng, Ruonan, Huang, Jiarui, He, Meng, Wang, Yuhan, Guo, Zonghao, Sun, Liankun, Chen, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305755/ https://www.ncbi.nlm.nih.gov/pubmed/30619480 http://dx.doi.org/10.3389/fgene.2018.00663 |
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