Knockdown of nucleophosmin 1 suppresses proliferation of triple-negative breast cancer cells through activating CDH1/Skp2/p27kip1 pathway

BACKGROUND: NPM1 is a multifunctional phosphoprotein that commutes between the cytoplasm and nucleus in cell cycle process, which appears to be actively involved in tumorigenesis. Herein, we sought to investigate the possible role and prognostic value of NPM1 in triple-negative breast cancer (TNBC)....

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Detalles Bibliográficos
Autores principales: Zeng, De, Xiao, Yingsheng, Zhu, Jianling, Peng, Chunyan, Liang, Weiquan, Lin, Haoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306051/
https://www.ncbi.nlm.nih.gov/pubmed/30613163
http://dx.doi.org/10.2147/CMAR.S191176

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