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Establishment of a conditional TALEN system using the translational enhancer dMac3 and an inducible promoter activated by glucocorticoid treatment to increase the frequency of targeted mutagenesis in plants

Transcription activator-like effector nuclease (TALEN) is an artificial nuclease that causes DNA cleavage at the target site and induces few off-target reactions because of its high sequence specificity. Powerful and variable tools using TALENs can be used in practical applications and may facilitat...

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Detalles Bibliográficos
Autores principales: Onodera, Hitomi, Shingu, Saeko, Ohnuma, Mariko, Horie, Takaaki, Kihira, Miho, Kusano, Hiroaki, Teramura, Hiroshi, Shimada, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306166/
https://www.ncbi.nlm.nih.gov/pubmed/30586438
http://dx.doi.org/10.1371/journal.pone.0208959