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Establishment of a conditional TALEN system using the translational enhancer dMac3 and an inducible promoter activated by glucocorticoid treatment to increase the frequency of targeted mutagenesis in plants
Transcription activator-like effector nuclease (TALEN) is an artificial nuclease that causes DNA cleavage at the target site and induces few off-target reactions because of its high sequence specificity. Powerful and variable tools using TALENs can be used in practical applications and may facilitat...
Autores principales: | Onodera, Hitomi, Shingu, Saeko, Ohnuma, Mariko, Horie, Takaaki, Kihira, Miho, Kusano, Hiroaki, Teramura, Hiroshi, Shimada, Hiroaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306166/ https://www.ncbi.nlm.nih.gov/pubmed/30586438 http://dx.doi.org/10.1371/journal.pone.0208959 |
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