A TNFSF13B functional variant is not involved in systemic sclerosis and giant cell arteritis susceptibility

BACKGROUND: The TNFSF13B (TNF superfamily member 13b) gene encodes BAFF, a cytokine with a crucial role in the differentiation and activation of B cells. An insertion-deletion variant (GCTGT→A) of this gene, leading to increased levels of BAFF, has been recently implicated in the genetic predisposit...

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Detalles Bibliográficos
Autores principales: González-Serna, David, Carmona, Elio G., Ortego-Centeno, Norberto, Simeón, Carmen P., Solans, Roser, Hernández-Rodríguez, José, Tolosa, Carlos, Castañeda, Santos, Narváez, Javier, Martinez-Valle, Ferran, Witte, Torsten, Neumann, Thomas, Holle, Julia, Beretta, Lorenzo, Boiardi, Luigi, Emmi, Giacomo, Cimmino, Marco A., Vaglio, Augusto, Herrick, Ariane L., Denton, Christopher P., Salvarani, Carlo, Cid, María C., Morgan, Ann W., Fonseca, Carmen, González-Gay, Miguel A., Martín, Javier, Márquez, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306228/
https://www.ncbi.nlm.nih.gov/pubmed/30586461
http://dx.doi.org/10.1371/journal.pone.0209343

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