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Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum
BACKGROUND: The study of Onchocerca volvulus has been limited by its host range, with only humans and non-human primates shown to be susceptible to the full life cycle infection. Small animal models that support the development of adult parasites have not been identified. METHODOLOGY/PRINCIPAL FINDI...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306240/ https://www.ncbi.nlm.nih.gov/pubmed/30540742 http://dx.doi.org/10.1371/journal.pntd.0006977 |