SRSF1 modulates PTPMT1 alternative splicing to regulate lung cancer cell radioresistance

BACKGROUND: Radioresistance is the major cause of cancer treatment failure. Additionally, splicing dysregulation plays critical roles in tumorigenesis. However, the involvement of alternative splicing in resistance of cancer cells to radiotherapy remains elusive. We sought to investigate the key rol...

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Detalles Bibliográficos
Autores principales: Sheng, Junxiu, Zhao, Qingzhi, Zhao, Jinyao, Zhang, Wenjing, Sun, Yu, Qin, Pan, Lv, Yuesheng, Bai, Lu, Yang, Quan, Chen, Lei, Qi, Yangfan, Zhang, Ge, Zhang, Lin, Gu, Chundong, Deng, Xiaoqin, Liu, Han, Meng, Songshu, Gu, Hong, Liu, Quentin, Coulson, Judy M., Li, Xiaoling, Sun, Bing, Wang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306353/
https://www.ncbi.nlm.nih.gov/pubmed/30429088
http://dx.doi.org/10.1016/j.ebiom.2018.11.007

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