Phloretin Prevents Diabetic Cardiomyopathy by Dissociating Keap1/Nrf2 Complex and Inhibiting Oxidative Stress

Hyperglycemia induces chronic inflammation and oxidative stress in cardiomyocyte, which are the main pathological changes of diabetic cardiomyopathy (DCM). Treatment aimed at these processes may be beneficial in DCM. Phloretin (PHL), a promising natural product, has many pharmacological activities,...

Descripción completa

Detalles Bibliográficos
Autores principales: Ying, Yin, Jin, Jiye, Ye, Li, Sun, Pingping, Wang, Hui, Wang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306411/
https://www.ncbi.nlm.nih.gov/pubmed/30619098
http://dx.doi.org/10.3389/fendo.2018.00774

Ejemplares similares

Ejemplares similares