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Mas-Related G Protein-Coupled Receptor-X2 (MRGPRX2) in Drug Hypersensitivity Reactions

The human ortholog MRGPRX2 and the mice ortholog, Mrgprb2 are activated by basic secretagogues and neurokinins. A number of commonly used small-molecule drugs (e.g., neuromuscular blocking agents, fluoroquinolones, vancomycin) have been recently shown to activate these receptors under in vitro exper...

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Detalles Bibliográficos
Autores principales:	Porebski, Grzegorz, Kwiecien, Kamila, Pawica, Magdalena, Kwitniewski, Mateusz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306423/ https://www.ncbi.nlm.nih.gov/pubmed/30619367 http://dx.doi.org/10.3389/fimmu.2018.03027

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