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Regulation of Effector and Memory CD8 T Cell Differentiation by IL-2—A Balancing Act
Interleukin-2 (IL-2) regulates key aspects of CD8 T cell biology–signaling through distinct pathways IL-2 triggers critical metabolic and transcriptional changes that lead to a spectrum of physiological outcomes such as cell survival, proliferation, and effector differentiation. In addition to drivi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306427/ https://www.ncbi.nlm.nih.gov/pubmed/30619342 http://dx.doi.org/10.3389/fimmu.2018.02987 |