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Regulation of Effector and Memory CD8 T Cell Differentiation by IL-2—A Balancing Act

Interleukin-2 (IL-2) regulates key aspects of CD8 T cell biology–signaling through distinct pathways IL-2 triggers critical metabolic and transcriptional changes that lead to a spectrum of physiological outcomes such as cell survival, proliferation, and effector differentiation. In addition to drivi...

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Detalles Bibliográficos
Autores principales:	Kalia, Vandana, Sarkar, Surojit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306427/ https://www.ncbi.nlm.nih.gov/pubmed/30619342 http://dx.doi.org/10.3389/fimmu.2018.02987

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