Salidroside improves the hypoxic tumor microenvironment and reverses the drug resistance of platinum drugs via HIF-1α signaling pathway

BACKGROUND: Hypoxia commonly occurs in solid tumors. The hypoxia in the center of solid tumors considerably decreases the chemosensitivity of tumor cells and induces epithelial–mesenchymal transition (EMT) as well as drug resistance of antitumor drugs. METHODS: Here, the effects of salidroside (Sal)...

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Detalles Bibliográficos
Autores principales: Qin, Yuan, Liu, Hui-juan, Li, Meng, Zhai, Deng-hui, Tang, Yuan-hao, Yang, Lan, Qiao, Kai-liang, Yang, Jia-huan, Zhong, Wei-long, Zhang, Qiang, Liu, Yan-rong, Yang, Guang, Sun, Tao, Yang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306459/
https://www.ncbi.nlm.nih.gov/pubmed/30396856
http://dx.doi.org/10.1016/j.ebiom.2018.10.069

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