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Impact of PCSK9 loss-of-function genotype on 1-year mortality and recurrent infection in sepsis survivors

BACKGROUND: Reduced activity of proprotein convertase subtilisin/kexin type 9 (PCSK9) has been associated with decreased short-term death in patients with septic shock. Whether PCSK9 genotype influences long-term outcomes in sepsis survivors is unknown. METHODS: We evaluated the impact of PCSK9 loss...

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Detalles Bibliográficos
Autores principales:	Genga, Kelly Roveran, Lo, Cody, Cirstea, Mihai S., Leitao Filho, Fernando Sergio, Walley, Keith R., Russell, James A., Linder, Adam, Francis, Gordon A., Boyd, John H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306489/ https://www.ncbi.nlm.nih.gov/pubmed/30473376 http://dx.doi.org/10.1016/j.ebiom.2018.11.032

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