Double Infection With Leishmania tropica and L. major in an HIV Patient Controlled With High Doses of Amphotericin B

We present a unique case of disseminated Leishmaniasis in an HIV patient. Two different Leishmania species were identified by genomic sequencing in both bone marrow and skin. The Leishmania infection could be suppressed but not cured, despite a high dose of amphotericin B of nearly 65 g over more th...

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Autores principales: Al Balushi, Asma, Khamis, Faryal, Klaassen, Corné H W, Gangneux, Jean-Pierre, Van Hellemond, Jaap J, Petersen, Eskild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306567/
https://www.ncbi.nlm.nih.gov/pubmed/30619911
http://dx.doi.org/10.1093/ofid/ofy323
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author Al Balushi, Asma
Khamis, Faryal
Klaassen, Corné H W
Gangneux, Jean-Pierre
Van Hellemond, Jaap J
Petersen, Eskild
author_facet Al Balushi, Asma
Khamis, Faryal
Klaassen, Corné H W
Gangneux, Jean-Pierre
Van Hellemond, Jaap J
Petersen, Eskild
author_sort Al Balushi, Asma
collection PubMed
description We present a unique case of disseminated Leishmaniasis in an HIV patient. Two different Leishmania species were identified by genomic sequencing in both bone marrow and skin. The Leishmania infection could be suppressed but not cured, despite a high dose of amphotericin B of nearly 65 g over more than 6 years.
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spelling pubmed-63065672019-01-07 Double Infection With Leishmania tropica and L. major in an HIV Patient Controlled With High Doses of Amphotericin B Al Balushi, Asma Khamis, Faryal Klaassen, Corné H W Gangneux, Jean-Pierre Van Hellemond, Jaap J Petersen, Eskild Open Forum Infect Dis Brief Report We present a unique case of disseminated Leishmaniasis in an HIV patient. Two different Leishmania species were identified by genomic sequencing in both bone marrow and skin. The Leishmania infection could be suppressed but not cured, despite a high dose of amphotericin B of nearly 65 g over more than 6 years. Oxford University Press 2018-12-07 /pmc/articles/PMC6306567/ /pubmed/30619911 http://dx.doi.org/10.1093/ofid/ofy323 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Al Balushi, Asma
Khamis, Faryal
Klaassen, Corné H W
Gangneux, Jean-Pierre
Van Hellemond, Jaap J
Petersen, Eskild
Double Infection With Leishmania tropica and L. major in an HIV Patient Controlled With High Doses of Amphotericin B
title Double Infection With Leishmania tropica and L. major in an HIV Patient Controlled With High Doses of Amphotericin B
title_full Double Infection With Leishmania tropica and L. major in an HIV Patient Controlled With High Doses of Amphotericin B
title_fullStr Double Infection With Leishmania tropica and L. major in an HIV Patient Controlled With High Doses of Amphotericin B
title_full_unstemmed Double Infection With Leishmania tropica and L. major in an HIV Patient Controlled With High Doses of Amphotericin B
title_short Double Infection With Leishmania tropica and L. major in an HIV Patient Controlled With High Doses of Amphotericin B
title_sort double infection with leishmania tropica and l. major in an hiv patient controlled with high doses of amphotericin b
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306567/
https://www.ncbi.nlm.nih.gov/pubmed/30619911
http://dx.doi.org/10.1093/ofid/ofy323
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