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Estimation of salivary Candida albicans counts in asthmatic adult patients taking anti-asthmatic medication for 3–5 years

BACKGROUND: Bronchial asthma is a chronic inflammatory disease of airways. The disease itself along with the principal medication used makes the oral cavity susceptible to most common opportunistic infection, i.e., oral candidiasis. There are many species of Candida causing oral candidiasis, but the...

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Autores principales: Alka, Kumari, Amberkar, Vikram S, Mohan Kumar, K P, Nandini, D B, Vidyasagar, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306586/
https://www.ncbi.nlm.nih.gov/pubmed/30651678
http://dx.doi.org/10.4103/jomfp.JOMFP_36_17
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author Alka, Kumari
Amberkar, Vikram S
Mohan Kumar, K P
Nandini, D B
Vidyasagar, B
author_facet Alka, Kumari
Amberkar, Vikram S
Mohan Kumar, K P
Nandini, D B
Vidyasagar, B
author_sort Alka, Kumari
collection PubMed
description BACKGROUND: Bronchial asthma is a chronic inflammatory disease of airways. The disease itself along with the principal medication used makes the oral cavity susceptible to most common opportunistic infection, i.e., oral candidiasis. There are many species of Candida causing oral candidiasis, but the most prevalent among them is Candida albicans. Hence, assessing C. albicans count in response to disease and its treatment is necessary. This enables us to educate asthma patients about side effects of medication and highlight the necessity for oral health care, thereby improving their quality of life. AIMS: The present study aims to evaluate the effects of asthma and its medication on C. albicans count in saliva samples of asthmatic adult patients taking medication for 3–5 years and compare C. albicans count in saliva samples among cases and controls. MATERIALS AND METHODS: Thirty asthmatic adults taking medication for asthma since 3–5 years' age ranging from 20 to 50 years and equal number of age- and sex-matched healthy participants were included in the study. In both groups, saliva was collected and inoculated on Sabouraud Dextrose Agar culture plates for estimation of C. albicans counts. C. albicans counts were assessed in colony-forming unit/milliliter. STATISTICAL ANALYSIS: Mann–Whitney U-test and Fisher's exact t-test were used. RESULTS: The C. albicans count is significantly higher among asthmatics than healthy individuals. CONCLUSIONS: The present study concludes that there is increased candidal growth among asthmatics as compared to their normal healthy counterpart.
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spelling pubmed-63065862019-01-16 Estimation of salivary Candida albicans counts in asthmatic adult patients taking anti-asthmatic medication for 3–5 years Alka, Kumari Amberkar, Vikram S Mohan Kumar, K P Nandini, D B Vidyasagar, B J Oral Maxillofac Pathol Original Article BACKGROUND: Bronchial asthma is a chronic inflammatory disease of airways. The disease itself along with the principal medication used makes the oral cavity susceptible to most common opportunistic infection, i.e., oral candidiasis. There are many species of Candida causing oral candidiasis, but the most prevalent among them is Candida albicans. Hence, assessing C. albicans count in response to disease and its treatment is necessary. This enables us to educate asthma patients about side effects of medication and highlight the necessity for oral health care, thereby improving their quality of life. AIMS: The present study aims to evaluate the effects of asthma and its medication on C. albicans count in saliva samples of asthmatic adult patients taking medication for 3–5 years and compare C. albicans count in saliva samples among cases and controls. MATERIALS AND METHODS: Thirty asthmatic adults taking medication for asthma since 3–5 years' age ranging from 20 to 50 years and equal number of age- and sex-matched healthy participants were included in the study. In both groups, saliva was collected and inoculated on Sabouraud Dextrose Agar culture plates for estimation of C. albicans counts. C. albicans counts were assessed in colony-forming unit/milliliter. STATISTICAL ANALYSIS: Mann–Whitney U-test and Fisher's exact t-test were used. RESULTS: The C. albicans count is significantly higher among asthmatics than healthy individuals. CONCLUSIONS: The present study concludes that there is increased candidal growth among asthmatics as compared to their normal healthy counterpart. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6306586/ /pubmed/30651678 http://dx.doi.org/10.4103/jomfp.JOMFP_36_17 Text en Copyright: © 2018 Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Alka, Kumari
Amberkar, Vikram S
Mohan Kumar, K P
Nandini, D B
Vidyasagar, B
Estimation of salivary Candida albicans counts in asthmatic adult patients taking anti-asthmatic medication for 3–5 years
title Estimation of salivary Candida albicans counts in asthmatic adult patients taking anti-asthmatic medication for 3–5 years
title_full Estimation of salivary Candida albicans counts in asthmatic adult patients taking anti-asthmatic medication for 3–5 years
title_fullStr Estimation of salivary Candida albicans counts in asthmatic adult patients taking anti-asthmatic medication for 3–5 years
title_full_unstemmed Estimation of salivary Candida albicans counts in asthmatic adult patients taking anti-asthmatic medication for 3–5 years
title_short Estimation of salivary Candida albicans counts in asthmatic adult patients taking anti-asthmatic medication for 3–5 years
title_sort estimation of salivary candida albicans counts in asthmatic adult patients taking anti-asthmatic medication for 3–5 years
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306586/
https://www.ncbi.nlm.nih.gov/pubmed/30651678
http://dx.doi.org/10.4103/jomfp.JOMFP_36_17
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