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Neuroprotective Effects of Cyclosporine in a Porcine Pre-Clinical Trial of Focal Traumatic Brain Injury
Mitochondrial dysfunction is thought to be a hallmark of traumatic brain injury (TBI) and plays a pivotal role in the resulting cellular injury. Cyclophilin D–mediated activation of the mitochondrial permeability transition pore has been suggested to contribute to this secondary injury cascade. Cycl...
Autores principales: | Karlsson, Michael, Pukenas, Bryan, Chawla, Sanjeev, Ehinger, Johannes K., Plyler, Ross, Stolow, Madeline, Gabello, Melissa, Hugerth, Matilda, Elmér, Eskil, Hansson, Magnus J., Margulies, Susan, Kilbaugh, Todd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306685/ https://www.ncbi.nlm.nih.gov/pubmed/29929438 http://dx.doi.org/10.1089/neu.2018.5706 |
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