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The Prenatal Microbiome: A New Player for Human Health

The last few years have featured an increasing interest in the study of the human microbiome and its correlations with health status. Indeed, technological advances have allowed the study of microbial communities to reach a previously unthinkable sensitivity, showing the presence of microbes also in...

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Detalles Bibliográficos
Autor principal: D’Argenio, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306741/
https://www.ncbi.nlm.nih.gov/pubmed/30544936
http://dx.doi.org/10.3390/ht7040038
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author D’Argenio, Valeria
author_facet D’Argenio, Valeria
author_sort D’Argenio, Valeria
collection PubMed
description The last few years have featured an increasing interest in the study of the human microbiome and its correlations with health status. Indeed, technological advances have allowed the study of microbial communities to reach a previously unthinkable sensitivity, showing the presence of microbes also in environments usually considered as sterile. In this scenario, microbial communities have been described in the amniotic fluid, the umbilical blood cord, and the placenta, denying a dogma of reproductive medicine that considers the uterus like a sterile womb. This prenatal microbiome may play a role not only in fetal development but also in the predisposition to diseases that may develop later in life, and also in adulthood. Thus, the aim of this review is to report the current knowledge regarding the prenatal microbiome composition, its association with pathological processes, and the future perspectives regarding its manipulation for healthy status promotion and maintenance.
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spelling pubmed-63067412019-01-03 The Prenatal Microbiome: A New Player for Human Health D’Argenio, Valeria High Throughput Review The last few years have featured an increasing interest in the study of the human microbiome and its correlations with health status. Indeed, technological advances have allowed the study of microbial communities to reach a previously unthinkable sensitivity, showing the presence of microbes also in environments usually considered as sterile. In this scenario, microbial communities have been described in the amniotic fluid, the umbilical blood cord, and the placenta, denying a dogma of reproductive medicine that considers the uterus like a sterile womb. This prenatal microbiome may play a role not only in fetal development but also in the predisposition to diseases that may develop later in life, and also in adulthood. Thus, the aim of this review is to report the current knowledge regarding the prenatal microbiome composition, its association with pathological processes, and the future perspectives regarding its manipulation for healthy status promotion and maintenance. MDPI 2018-12-11 /pmc/articles/PMC6306741/ /pubmed/30544936 http://dx.doi.org/10.3390/ht7040038 Text en © 2018 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
D’Argenio, Valeria
The Prenatal Microbiome: A New Player for Human Health
title The Prenatal Microbiome: A New Player for Human Health
title_full The Prenatal Microbiome: A New Player for Human Health
title_fullStr The Prenatal Microbiome: A New Player for Human Health
title_full_unstemmed The Prenatal Microbiome: A New Player for Human Health
title_short The Prenatal Microbiome: A New Player for Human Health
title_sort prenatal microbiome: a new player for human health
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306741/
https://www.ncbi.nlm.nih.gov/pubmed/30544936
http://dx.doi.org/10.3390/ht7040038
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